{"database":"GEO","file_versions":[{"headers":{"Content-Type":["application/json"]},"body":{"files":{"Other":["ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE293nnn/GSE293704/"]},"type":"primary"},"statusCode":"OK","statusCodeValue":200}],"scores":null,"additional":{"omics_type":["Transcriptomics"],"species":["Mus musculus"],"gds_type":["Expression profiling by high throughput sequencing"],"full_dataset_link":["https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE293704"],"repository":["GEO"],"entry_type":["GSE"],"additional_accession":[]},"is_claimable":false,"name":"Transcriptome analysis in the prefrontal cortex of Tbr1+/K228E heterozygous mice treated with drug","description":"Autism spectrum disorders (ASD) affect ~2.8% of the population, but the underlying biological mechanisms remain poorly understood, largely due to significant genetic heterogeneity. Mouse models have identified numerous candidate mechanisms; however, whether these can be grouped into functionally coherent subtypes remains unclear, limiting targeted, mechanism-based treatments. We analyzed prefrontal cortex transcriptomes from 17 distinct ASD mouse models, encompassing both sexes, under baseline and two separate drug-treatment conditions, totaling 1,008 mice across 204 groups.","dates":{"publication":"2026/07/28"},"accession":"GSE293704","cross_references":{"GSM":["GSM8888863","GSM8888864","GSM8888865","GSM8888866","GSM8888860","GSM8888861","GSM8888862","GSM8888827","GSM8888828","GSM8888829","GSM8888867","GSM8888868","GSM8888824","GSM8888825","GSM8888869","GSM8888826","GSM8888852","GSM8888853","GSM8888854","GSM8888855","GSM8888850","GSM8888851","GSM8888856","GSM8888857","GSM8888858","GSM8888859","GSM8888880","GSM8888841","GSM8888842","GSM8888843","GSM8888844","GSM8888881","GSM8888882","GSM8888883","GSM8888840","GSM8888849","GSM8888845","GSM8888846","GSM8888847","GSM8888848","GSM8888874","GSM8888830","GSM8888831","GSM8888875","GSM8888832","GSM8888876","GSM8888877","GSM8888833","GSM8888870","GSM8888871","GSM8888872","GSM8888873","GSM8888838","GSM8888839","GSM8888834","GSM8888878","GSM8888835","GSM8888879","GSM8888836","GSM8888837"],"GPL":["24247"],"GSE":["293704"],"taxon":["Mus musculus"]}}