{"database":"GEO","file_versions":[{"headers":{"Content-Type":["application/json"]},"body":{"files":{"Other":["ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE294nnn/GSE294123/"]},"type":"primary"},"statusCode":"OK","statusCodeValue":200}],"scores":null,"additional":{"omics_type":["Transcriptomics"],"species":["Mus musculus"],"gds_type":["Expression profiling by high throughput sequencing"],"full_dataset_link":["https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE294123"],"repository":["GEO"],"entry_type":["GSE"],"additional_accession":[]},"is_claimable":false,"name":"Transcriptome analysis in the prefrontal cortex of Shank2 heterozygous mice treated with drug","description":"Autism spectrum disorders (ASD) affect ~2.8% of the population, but the underlying biological mechanisms remain poorly understood, largely due to significant genetic heterogeneity. Mouse models have identified numerous candidate mechanisms; however, whether these can be grouped into functionally coherent subtypes remains unclear, limiting targeted, mechanism-based treatments. We analyzed prefrontal cortex transcriptomes from 17 distinct ASD mouse models, encompassing both sexes, under baseline and two separate drug-treatment conditions, totaling 1,008 mice across 204 groups.","dates":{"publication":"2026/07/28"},"accession":"GSE294123","cross_references":{"GSM":["GSM8898981","GSM8898982","GSM8898980","GSM8898985","GSM8898986","GSM8898983","GSM8898984","GSM8898989","GSM8898987","GSM8898988","GSM8899030","GSM8899026","GSM8899025","GSM8899024","GSM8899023","GSM8898974","GSM8899029","GSM8898975","GSM8899028","GSM8899027","GSM8898978","GSM8898979","GSM8898976","GSM8898977","GSM8899022","GSM8899021","GSM8899020","GSM8899015","GSM8899014","GSM8899013","GSM8899012","GSM8899019","GSM8899018","GSM8899017","GSM8899016","GSM8899011","GSM8899010","GSM8898992","GSM8899004","GSM8899003","GSM8898993","GSM8898990","GSM8899002","GSM8898991","GSM8899001","GSM8899008","GSM8898996","GSM8898997","GSM8899007","GSM8898994","GSM8899006","GSM8899005","GSM8898995","GSM8898998","GSM8899009","GSM8898999","GSM8899000"],"GPL":["24247"],"GSE":["294123"],"taxon":["Mus musculus"]}}