{"database":"GEO","file_versions":[{"headers":{"Content-Type":["application/json"]},"body":{"files":{"Other":["ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE294nnn/GSE294127/"]},"type":"primary"},"statusCode":"OK","statusCodeValue":200}],"scores":null,"additional":{"omics_type":["Transcriptomics"],"species":["Mus musculus"],"gds_type":["Expression profiling by high throughput sequencing"],"full_dataset_link":["https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE294127"],"repository":["GEO"],"entry_type":["GSE"],"additional_accession":[]},"is_claimable":false,"name":"Transcriptome analysis in the prefrontal cortex of Ank2 heterozygous mice treated with drug","description":"Autism spectrum disorders (ASD) affect ~2.8% of the population, but the underlying biological mechanisms remain poorly understood, largely due to significant genetic heterogeneity. Mouse models have identified numerous candidate mechanisms; however, whether these can be grouped into functionally coherent subtypes remains unclear, limiting targeted, mechanism-based treatments. We analyzed prefrontal cortex transcriptomes from 17 distinct ASD mouse models, encompassing both sexes, under baseline and two separate drug-treatment conditions, totaling 1,008 mice across 204 groups.","dates":{"publication":"2026/07/28"},"accession":"GSE294127","cross_references":{"GSM":["GSM8899114","GSM8899113","GSM8899112","GSM8899111","GSM8899118","GSM8899117","GSM8899116","GSM8899115","GSM8899119","GSM8899150","GSM8899110","GSM8899153","GSM8899152","GSM8899151","GSM8899103","GSM8899147","GSM8899102","GSM8899146","GSM8899145","GSM8899101","GSM8899100","GSM8899144","GSM8899107","GSM8899106","GSM8899105","GSM8899149","GSM8899148","GSM8899104","GSM8899109","GSM8899108","GSM8899143","GSM8899142","GSM8899141","GSM8899140","GSM8899136","GSM8899135","GSM8899134","GSM8899133","GSM8899139","GSM8899138","GSM8899137","GSM8899095","GSM8899099","GSM8899132","GSM8899131","GSM8899098","GSM8899097","GSM8899130","GSM8899096","GSM8899125","GSM8899124","GSM8899123","GSM8899122","GSM8899129","GSM8899128","GSM8899127","GSM8899126","GSM8899121","GSM8899120"],"GPL":["24247"],"GSE":["294127"],"taxon":["Mus musculus"]}}