GEOapplication/xmlftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE294nnn/GSE294127/primaryOK200TranscriptomicsMus musculusExpression profiling by high throughput sequencinghttps://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE294127GEOGSEfalseTranscriptome analysis in the prefrontal cortex of Ank2 heterozygous mice treated with drugAutism spectrum disorders (ASD) affect ~2.8% of the population, but the underlying biological mechanisms remain poorly understood, largely due to significant genetic heterogeneity. Mouse models have identified numerous candidate mechanisms; however, whether these can be grouped into functionally coherent subtypes remains unclear, limiting targeted, mechanism-based treatments. We analyzed prefrontal cortex transcriptomes from 17 distinct ASD mouse models, encompassing both sexes, under baseline and two separate drug-treatment conditions, totaling 1,008 mice across 204 groups.2026/07/28GSE294127GSM8899114GSM8899113GSM8899112GSM8899111GSM8899118GSM8899117GSM8899116GSM8899115GSM8899119GSM8899150GSM8899110GSM8899153GSM8899152GSM8899151GSM8899103GSM8899147GSM8899102GSM8899146GSM8899145GSM8899101GSM8899100GSM8899144GSM8899107GSM8899106GSM8899105GSM8899149GSM8899148GSM8899104GSM8899109GSM8899108GSM8899143GSM8899142GSM8899141GSM8899140GSM8899136GSM8899135GSM8899134GSM8899133GSM8899139GSM8899138GSM8899137GSM8899095GSM8899099GSM8899132GSM8899131GSM8899098GSM8899097GSM8899130GSM8899096GSM8899125GSM8899124GSM8899123GSM8899122GSM8899129GSM8899128GSM8899127GSM8899126GSM8899121GSM889912024247294127Mus musculus