GEOapplication/xmlftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE294nnn/GSE294583/primaryOK200TranscriptomicsMus musculusExpression profiling by high throughput sequencinghttps://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE294583GEOGSEfalseCold-inducible RNA-binding protein promotes lung fibroblast activation via TLR2/4-dependent IL-6 signaling: implications in pulmonary fibrosisThis study investigates the role of Cold-inducible RNA-binding protein (CIRBP) in the pathogenesis of pulmonary fibrosis. Using RNA-seq, we analyzed gene expression changes in primary mouse lung fibroblasts stimulated with recombinant CIRBP or PBS control. CIRBP significantly upregulated cytokine-related gene expression, including IL-6, and promoted collagen production and fibroblast proliferation via TLR2/4 pathways.2026/03/11GSE294583GSM8911845GSM8911844GSM8911843GSM8911842GSM8911847GSM891184624247294583Mus musculus[41667819]