GEOapplication/xmlftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE294nnn/GSE294777/primaryOK200TranscriptomicsMus musculusExpression profiling by high throughput sequencinghttps://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE294777GEOGSEfalseEarly Intervention of the PKC-Hippo Signaling Alleviates Post-Traumatic OsteoarthritisPost-traumatic osteoarthritis (PTOA) is a progressive joint disease triggered by mechanical injury and characterized by inflammation and cartilage degradation. The Hippo signaling pathway and its upstream regulator PKCζ have emerged as key modulators of mechano-inflammatory responses in chondrocytes. This study aimed to investigate the dynamic regulation of the PKC-Hippo signaling axis following joint injury and to evaluate the therapeutic potential of targeting this pathway in early PTOA.2026/04/17GSE294777GSM8919385GSM8919384GSM8919383GSM8919382GSM8919381GSM8919380GSM8919379GSM8919378GSM891937728457294777Mus musculus