GEOapplication/xmlftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE295nnn/GSE295204/primaryOK200TranscriptomicsHomo sapiensExpression profiling by high throughput sequencinghttps://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE295204GEOGSEfalseTranscriptomic profiling of iPSC-derived microglia(iMGL) reveals FGL2-mediated Aβ uptake impairment and argatroban rescue associated with rs73375428 genotype.To elucidate how the rs73375428 major allele impairs Aβ uptake and how argatroban rescues this impairment independently of thrombin inhibition, we performed RNA sequencing and bioinformatic analyses in iPSC-derived microglia(iMGL). These datasets provide insight into transcriptomic changes associated with FGL2 modulation and Alzheimer’s disease risk.2026/04/21GSE295204GSM8943560GSM8943559GSM8943557GSM8943558GSM8943555GSM8943556GSM8943553GSM8943554GSM894355224676295204Homo sapiens