{"database":"GEO","file_versions":[{"headers":{"Content-Type":["application/json"]},"body":{"files":{"Other":["ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE295nnn/GSE295230/"]},"type":"primary"},"statusCode":"OK","statusCodeValue":200}],"scores":null,"additional":{"omics_type":["Transcriptomics"],"species":["Mus musculus"],"gds_type":["Expression profiling by high throughput sequencing"],"full_dataset_link":["https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE295230"],"repository":["GEO"],"entry_type":["GSE"],"additional_accession":[]},"is_claimable":false,"name":"MASH Mouse Model Transcriptomic Characteristics","description":"Metabolic dysfunction-associated fatty liver disease (MAFLD) is currently the most common liver disease worldwide, characterized primarily by liver fat accumulation. The progression of MAFLD occurs in a series of stages, from simple steatosis to metabolic dysfunction-associated steatohepatitis (MASH), and eventually to cirrhosis.The MASH mouse model developed pathological fat deposition and inflammatory infiltration after being subjected to a methionine/choline-deficient (MCD) diet for 6 weeks. Transcriptome sequencing was then conducted to analyze differentially expressed genes.","dates":{"publication":"2026/07/01"},"accession":"GSE295230","cross_references":{"GSM":["GSM8944034","GSM8944033","GSM8944032","GSM8944037","GSM8944036","GSM8944035"],"GPL":["34290"],"GSE":["295230"],"taxon":["Mus musculus"]}}