{"database":"GEO","file_versions":[],"scores":null,"additional":{"omics_type":["Transcriptomics"],"species":["Sus scrofa"],"gds_type":["Expression profiling by high throughput sequencing"],"full_dataset_link":["https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE295679"],"repository":["GEO"],"entry_type":["GSE"],"additional_accession":[]},"is_claimable":false,"name":"Time-Resolved Transcriptomic Analysis of Mammary Ductal Development, Lactation Function Activation, and Glandular Involution in Sows","description":"To investigate the dynamic changes in gene expression during mammary gland development and lactation in sows, mammary tissue samples were collected from 30 multiparous crossbred half-sibling sows (Danish Landrace × Yorkshire) housed under standardized conditions. Samples were obtained at five critical physiological stages: mid-gestation (Day 70), late gestation (Day 110), early lactation (Day 2 postpartum), peak lactation (Day 10 postpartum), and early involution (Day 2 post-weaning), with six biological replicates per stage. Parenchymal mammary tissue (0.5–1 cm³) was excised from a defined location below the third pair of teats and rapidly snap-frozen in liquid nitrogen for RNA preservation. All instruments were treated with RNase inhibitors to ensure RNA integrity. The collected samples were stored at –80°C for subsequent total RNA extraction and transcriptome sequencing, providing a valuable resource for elucidating molecular mechanisms underlying mammary gland remodeling and lactation regulation in sows.","dates":{"publication":"2026/05/20"},"accession":"GSE295679","cross_references":{"GSM":["GSM8955001","GSM8954990","GSM8955000","GSM8954999","GSM8955007","GSM8954996","GSM8954995","GSM8955006","GSM8955009","GSM8954998","GSM8955008","GSM8954997","GSM8954992","GSM8955003","GSM8955002","GSM8954991","GSM8955005","GSM8954994","GSM8955004","GSM8954993","GSM8955010","GSM8955012","GSM8955011","GSM8955018","GSM8955017","GSM8955019","GSM8955014","GSM8955013","GSM8955016","GSM8955015"],"GPL":["19176"],"GSE":["295679"],"taxon":["Sus scrofa"],"PMID":["[41265484]"]}}