{"database":"GEO","file_versions":[{"headers":{"Content-Type":["application/json"]},"body":{"files":{"Other":["ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE295nnn/GSE295693/"]},"type":"primary"},"statusCode":"OK","statusCodeValue":200}],"scores":null,"additional":{"omics_type":["Genomics"],"species":["Homo sapiens"],"gds_type":["Non-coding RNA profiling by high throughput sequencing"],"full_dataset_link":["https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE295693"],"repository":["GEO"],"entry_type":["GSE"],"additional_accession":[]},"is_claimable":false,"name":"Small RNA sequencing of extracellular vesicles extracted from adipose tissue of healthy weight or obese human subjects","description":"We identified EVs as novel regulatory factors that mediate adipose tissue–brain communication and are crucial for the central control of whole-body energy homeostasis. Our findings reveal that AT-EVs and their cargo microRNAs (miRNAs) are crucial regulators of central leptin sensitivity. To identify the specific subtypes of miRNAs that responsible for central leptin-sensitizing, we examined the sRNA profiles of EVs extracted from adipose tissue of healthy weight and obese subjects by RNA deep sequencing.","dates":{"publication":"2026/04/10"},"accession":"GSE295693","cross_references":{"GSM":["GSM8955296","GSM8955295","GSM8955298","GSM8955297","GSM8955300","GSM8955299","GSM8955301"],"GPL":["16791"],"GSE":["295693"],"taxon":["Homo sapiens"],"PMID":["[41223857]"]}}