{"database":"GEO","file_versions":[{"headers":{"Content-Type":["application/json"]},"body":{"files":{"Other":["ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE296nnn/GSE296330/"]},"type":"primary"},"statusCode":"OK","statusCodeValue":200}],"scores":null,"additional":{"omics_type":["Other"],"species":["Mus musculus"],"gds_type":["Other"],"full_dataset_link":["https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE296330"],"repository":["GEO"],"entry_type":["GSE"],"additional_accession":[]},"is_claimable":false,"name":"Transcriptomic profiling of cancer-associated fibroblasts (CAFs)/activated-hepatic stellate cells (HSCs) of murine cholangiocarcinoma (CCA) by NanoString GeoMX DSP.","description":"To study whether targeting Cd274/PD-L1 of HSCs by Cre/loxP approach in mice altered HSC transcriptome, HSC activation into CAFs, CCA/HSC interactions, and CCA growth, portal vein injection of SB mouse CCA cells (1 million cells per mouse) was performed on two months old Cd274+/+Col1A1Cre mice and two months old Cd274F/FCol1A1Cre mice. Murine CCA sections were prepared for transcriptomic profiling with the NanoString GeoMix DSP","dates":{"publication":"2026/05/04"},"accession":"GSE296330","cross_references":{"GSM":["GSM8968696","GSM8968695","GSM8968698","GSM8968697","GSM8968700","GSM8968699"],"GPL":["30172"],"GSE":["296330"],"taxon":["Mus musculus"]}}