GEOapplication/xmlftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE296nnn/GSE296376/primaryOK200GenomicsGallus gallusGenome binding/occupancy profiling by high throughput sequencinghttps://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE296376GEOGSEfalseCTCF regulates chromatin accessibility of the HBAD gene promoter during erythroid differentiationChromatin structure undergoes dynamic rearrangements during cell differentiation. The architectural protein CTCF plays diverse roles in this process. Here, we demonstrate that a subset of gene promoters alters their chromatin accessibility profiles upon CTCF binding during differentiation of the chicken erythroblast cell line HD3. Furthermore, we show that CTCF contributes to establishing a specific 3D chromatin architecture in the α-globin multigenic domain prior to differentiation in HD3 cells.2026/04/29GSE296376GSM8969387GSM8969386GSM8969389GSM8969388GSM8969383GSM8969385GSM8969384GSM896939019005296376Gallus gallus