GEOapplication/xmlftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE296nnn/GSE296416/primaryOK200OtherGallus gallusOtherhttps://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE296416GEOGSEfalseCTCF regulates chromatin accessibility of the HBAD gene promoter during erythroid differentiation [UMI-4C]Chromatin structure undergoes dynamic rearrangements during cell differentiation. The architectural protein CTCF plays diverse roles in this process. Here, we demonstrate that a subset of gene promoters alters their chromatin accessibility profiles upon CTCF binding during differentiation of the chicken erythroblast cell line HD3. Furthermore, we show that CTCF contributes to establishing a specific 3D chromatin architecture in the α-globin multigenic domain prior to differentiation in HD3 cells.2026/04/29GSE296416GSM8970088GSM8970087GSM8970086GSM8970085GSM8970084GSM8970083GSM8970082GSM897008119005296416Gallus gallus