{"database":"GEO","file_versions":[{"headers":{"Content-Type":["application/json"]},"body":{"files":{"Other":["ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE296nnn/GSE296732/"]},"type":"primary"},"statusCode":"OK","statusCodeValue":200}],"scores":null,"additional":{"omics_type":["Transcriptomics"],"species":["Mus musculus"],"gds_type":["Expression profiling by high throughput sequencing"],"full_dataset_link":["https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE296732"],"repository":["GEO"],"entry_type":["GSE"],"additional_accession":[]},"is_claimable":false,"name":"SP5/8 transcription factors drive primary cilia formation","description":"Sp5/8 are tissue specific zinc finger transcription factors downstream of Wnt signaling pathway. Sp5/8 null embryos display severe posterior axis truncation resembling mutant phenotypes of Wnt/b-catenin signaling pathway. To address the role of Sp5/8 in gastrulation development, we differentiated R1 Wildtype (WT) and Sp5/8 dko Embryonic Stem Cells (ESCs) as gastruloids as described previously (Beccari, L. et al, 2018) to evaluate scRNA transcriptome analysis.","dates":{"publication":"2026/04/22"},"accession":"GSE296732","cross_references":{"GSM":["GSM8975432","GSM8975431"],"GPL":["34290"],"GSE":["296732"],"taxon":["Mus musculus"],"PMID":["[40875857]"]}}