GEOapplication/xmlftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE296nnn/GSE296902/primaryOK200TranscriptomicsMus musculusExpression profiling by high throughput sequencinghttps://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE296902GEOGSEfalseTarget macrophage SPP1 promtes CD8 T cell infiltrationsSPP1 in tumor associated macrophages (TAM) can inhibit the infiltration of CD8 T cells, promote tumor growth, and reduce the efficacy of ICI immunotherapy. Single cell (sc)-RNA sequencing data showed markedly increased CD8 T cells in the tumor tissues of SPP1fl/fl-Lyz2-icre mice compared to control SPP1fl/fl mice.2026/06/30GSE296902GSM8979630GSM897963124247296902Mus musculus