GEOMethylation profilingMus musculusMethylation profiling by high throughput sequencinghttps://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE297196GEOGSEfalsem6A RIP-seq of beta-cell s from liver-specific insulin receptor knockout (LIRKO) miceIn type 2 diabetes, pancreatic beta-cells fail to compensate for the presence of insulin resistance in target tissues. Identifying and studying innovative molecular mechanisms that control the beta-cell adaptation to insulin resistance represent an interesting line of research and are necessary. N6-Methyladenosine (m6A) is the most abundant modification in mRNA and is found virtually in all mammals. Through m6A-profiling of Control and LIRKO islets we aimed to identify the m6A landscape of the successful beta-cell adaption to insulin resistance.2026/05/14GSE297196GSM8985458GSM8985436GSM8985437GSM8985459GSM8985438GSM8985450GSM8985451GSM8985452GSM8985430GSM8985431GSM8985453GSM8985454GSM8985432GSM8985455GSM8985433GSM8985434GSM8985456GSM8985457GSM8985435GSM8985447GSM8985448GSM8985449GSM8985427GSM8985428GSM8985429GSM8985461GSM8985462GSM898546021103297196Mus musculus