{"database":"GEO","file_versions":[{"headers":{"Content-Type":["application/json"]},"body":{"files":{"Other":["ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE297nnn/GSE297804/"]},"type":"primary"},"statusCode":"OK","statusCodeValue":200}],"scores":null,"additional":{"omics_type":["Transcriptomics"],"species":["Homo sapiens"],"gds_type":["Expression profiling by array"],"full_dataset_link":["https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE297804"],"repository":["GEO"],"entry_type":["GSE"],"additional_accession":[]},"is_claimable":false,"name":"Expression profile of cells overexpressing genetic variants encoding XIAP with distinct subcellular localization.","description":"Messenger RNA (mRNA) samples from MCF-7 breast cancer cells transfected with the plasmid vectors: pEBB (empty vector), pEBB-HA-XIAPwild type (cytoplasmic XIAP expression), pEBB-HA-XIAPH467A (lack of ubiquitin ligase activity; cytoplasmic XIAP expression), pEBB-HA-XIAPΔRING (deletion of the RING domain; nuclear and cytoplasmic XIAP expression) and XIAPNLS (insertion of a nuclear localization signal; nuclear and cytoplasmic XIAP expression) were amplified, labeled and hybridized to the ClariomTM S Array human (Thermo Scientific, USA). Normalization and analysis of microarray data was performed using the Transcriptome Analysis Console (TAC) software (Affymetrix, USA).","dates":{"publication":"2026/06/01"},"accession":"GSE297804","cross_references":{"GSM":["GSM8999802","GSM8999803","GSM8999804","GSM8999805","GSM8999806"],"GPL":["23159"],"GSE":["297804"],"taxon":["Homo sapiens"]}}