GEOapplication/xmlftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE297nnn/GSE297810/primaryOK200TranscriptomicsHomo sapiensExpression profiling by high throughput sequencinghttps://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE297810GEOGSEfalseDifferentially expressed genes in HTR-8/SVneo cell overexpressing miR-26a-5p modulate invasion and migrationAberrant expression of microRNAs (miRNAs) is a critical factor in the pathogenesis of preeclampsia (PE). miR-26a-5p is a key regulatory miRNA that plays an important role in trophoblast cell function, which is essential during placental development. This study aims to investigate the impact of miR-26a-5p overexpression on the transcriptome of trophoblastic HTR-8/SVneo cells, a commonly used model for studying trophoblast functions in placentas collected from pregnancies complicated by PE. In this study, HTR-8/SVneo cells were transfected with 75 nM miR-26a-5p mimics, and RNA sequencing (RNA-seq) was employed to analyze alterations in gene expression.2026/05/18GSE297810GSM9000101GSM9000100GSM9000099GSM9000098GSM9000097GSM900009628038297810Homo sapiens