<HashMap><database>GEO</database><file_versions><headers><Content-Type>application/xml</Content-Type></headers><body><files><Other>ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE297nnn/GSE297875/</Other></files><type>primary</type></body><statusCode>OK</statusCode><statusCodeValue>200</statusCodeValue></file_versions><scores/><additional><omics_type>Transcriptomics</omics_type><species>Mus musculus</species><gds_type>Expression profiling by high throughput sequencing</gds_type><full_dataset_link>https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE297875</full_dataset_link><repository>GEO</repository><entry_type>GSE</entry_type></additional><is_claimable>false</is_claimable><name>Treatment of mouse breast cancer cell line 4T1 with cepharanthine for RNA-seq</name><description>Breast cancer remains a significant global health challenge, with the highly aggressive 4T1 mouse mammary carcinoma cell line serving as a common model for studying triple-negative breast cancer (TNBC) due to its metastatic potential and resistance to therapy. Cepharanthine (CEP), a natural bisbenzylisoquinoline alkaloid, has demonstrated anti-inflammatory, immunomodulatory, and anti-cancer properties in various malignancies. However, its molecular mechanisms in 4T1 cells remain poorly understood. In this study, we treated 4T1 cells with CEP and performed RNA sequencing (RNA-seq) to elucidate transcriptomic alterations induced by this compound.</description><dates><publication>2026/05/01</publication></dates><accession>GSE297875</accession><cross_references><GSM>GSM9001391</GSM><GSM>GSM9001392</GSM><GSM>GSM9001393</GSM><GSM>GSM9001394</GSM><GSM>GSM9001395</GSM><GSM>GSM9001396</GSM><GPL>24247</GPL><GSE>297875</GSE><taxon>Mus musculus</taxon></cross_references></HashMap>