{"database":"GEO","file_versions":[{"headers":{"Content-Type":["application/json"]},"body":{"files":{"Other":["ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE298nnn/GSE298039/"]},"type":"primary"},"statusCode":"OK","statusCodeValue":200}],"scores":null,"additional":{"omics_type":["Transcriptomics"],"species":["Mus musculus"],"gds_type":["Expression profiling by high throughput sequencing"],"full_dataset_link":["https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE298039"],"repository":["GEO"],"entry_type":["GSE"],"additional_accession":[]},"is_claimable":false,"name":"Transcriptome profiling of CT26 cells and de-differentiated CT26 cells induced by forced expresssion of Oct4 and SOX2 using RNA-sequencing.","description":"The core proeprty of cancer cells is neural stemness, which determines tumorigenicity and pluripotency. It has been reported that neural stem cells are uniquely immune-privileged, suggesting that neural stemness also confers cancer cells with the ability of immune evasion or immune privilege. CT26 is a mouse colon cancer cell line. We found that dedifferentiation of CT26 cells with overexpression of Oct4 and SOX2 enhanced neural stemness and decreased immunogenicity in cells.","dates":{"publication":"2026/05/31"},"accession":"GSE298039","cross_references":{"GSM":["GSM9005570","GSM9005571"],"GPL":["24247"],"GSE":["298039"],"taxon":["Mus musculus"]}}