GEOapplication/xmlftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE298nnn/GSE298553/primaryOK200GenomicsRattus norvegicusNon-coding RNA profiling by high throughput sequencinghttps://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE298553GEOGSEfalseSmall RNA sequencing of circulating exosomes from SD ratsAfter total RNA was extracted by Trizol reagent kit (Invitrogen, Carlsbad, CA,USA), the RNA molecules in a size range of 18–30nt were enriched by polyacrylamide gelelectrophoresis(PAGE). Then the 3’ adapters were added and the 36-48nt RNAs were enriched. The 5’ adapters were then ligated to the RNAs as well. The ligation products were reverse transcribed by PCR amplification and the 140-160bp size PCR products were enriched to generate a cDNA library and sequenced using Illumina HiSeq Xten by Gene Denovo Biotechnology Co. (Guangzhou, China).2026/04/01GSE298553GSM9017167GSM9017168GSM9017169GSM9017170GSM9017171GSM901717218694298553Rattus norvegicus[41878333]