GEOapplication/xmlftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE298nnn/GSE298703/primaryOK200TranscriptomicsMus musculusExpression profiling by high throughput sequencinghttps://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE298703GEOGSEfalseTpsb2-CreERT2 system did not alter mast cell viability or developmentThe selection of an appropriate Cre line is critical for ensuring the accuracy of cell type–specific investigations. We generated a Tpsb2-CreERT2 mouse line that enables precise and efficient labeling of target mast cells, with no detectable off-target recombination or cytotoxic effects, making it a reliable tool for lineage tracing and functional studies. To assess potential Cre-mediated toxicity, we performed transcriptomic analysis of peritoneal mast cells, which revealed no significant alterations in gene expression profiles, further supporting the importance of this model.2026/03/13GSE298703GSM9021236GSM9021237GSM9021241GSM9021240GSM9021238GSM902123928330298703Mus musculus[41195564]