GEOapplication/xmlftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE298nnn/GSE298793/primaryOK200TranscriptomicsMus musculusExpression profiling by high throughput sequencinghttps://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE298793GEOGSEfalseTime-restricted feeding blocks kidney fibrosis and damage through diminished CD8+ T cell infiltration in obese miceObesity is a major risk factor for chronic kidney disease. Our lab previously showed that a short-term (2 week) time restricted feeding (TRF) intervention in an established model of diet induced obesity (DIO) reduced kidney interstitial fibrosis, increased tubular brush border integrity, and decreased CD3+ T cell numbers. There is very little known about kidney damage and T cell inflammation in obesity. Single cell RNA sequencing was used to determine transcriptomes of CD45+ cells isolated from kidneys.2026/07/16GSE298793GSM9023409GSM9023406GSM9023405GSM9023408GSM902340724247298793Mus musculus