GEOapplication/xmlftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE298nnn/GSE298858/primary200OKTranscriptomicsMus musculusExpression profiling by high throughput sequencinghttps://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE298858GEOGSEfalseASK1-induces FGF21 expression in the liverIncreasing circulating fibroblast growth factor 21 (FGF21) concentrations may be an appealing strategy to prevent/treat obesity. Herein we identify apoptosis signal regulating kinase 1 (ASK1) as an inducer of hepatic FGF21 production. High fat diet (HFD)-fed liver-specific ASK1 overexpressing mice (ASK1+hep) revealed increased hepatic expression and circulating levels of FGF21.2026/08/05GSE298858GSM9025207GSM9025208GSM9025205GSM9025206GSM9025214GSM9025212GSM9025213GSM9025210GSM9025211GSM902520924247298858Mus musculus[42461584]