{"database":"GEO","file_versions":[{"headers":{"Content-Type":["application/json"]},"body":{"files":{"Other":["ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE298nnn/GSE298870/"]},"type":"primary"},"statusCode":"OK","statusCodeValue":200}],"scores":null,"additional":{"omics_type":["Transcriptomics"],"species":["Mus musculus"],"gds_type":["Expression profiling by high throughput sequencing"],"full_dataset_link":["https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE298870"],"repository":["GEO"],"entry_type":["GSE"],"additional_accession":[]},"is_claimable":false,"name":"Pharmacological inhibition of sclerostin protects bone from B-cell acute lymphoblastic leukemia-mediated destruction","description":"The cellular components of the BM microenvironment are known to play a role in the development of B-cell acute lymphoblastic leukemia (B-ALL). However, molecular differences between heathy osteoblastic cells (OBCs) and OBCs associated with B-ALL remain unclear. This study utilises bulk RNA-seq to evaluate the molecular signatures between the healthy OBCs and B-ALL-associated OBCs.","dates":{"publication":"2026/05/05"},"accession":"GSE298870","cross_references":{"GSM":["GSM9025359","GSM9025357","GSM9025358","GSM9025364","GSM9025362","GSM9025363","GSM9025360","GSM9025361"],"GPL":["23479"],"GSE":["298870"],"taxon":["Mus musculus"],"PMID":["[42038749]"]}}