{"database":"GEO","file_versions":[{"headers":{"Content-Type":["application/json"]},"body":{"files":{"Other":["ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE298nnn/GSE298918/"]},"type":"primary"},"statusCode":"OK","statusCodeValue":200}],"scores":null,"additional":{"omics_type":["Transcriptomics"],"species":["Staphylococcus aureus"],"gds_type":["Expression profiling by high throughput sequencing"],"full_dataset_link":["https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE298918"],"repository":["GEO"],"entry_type":["GSE"],"additional_accession":[]},"is_claimable":false,"name":"The role of PurR purine transcriptional repressor and Rae1 endoribonuclease in Erm-mediated macrolide resistance in methicilin-resistant Staphylococcus aureus.","description":"Differential gene expression between six S. aureus strains were determined by RNA-seq in 3 biological replicates.The six strains are ermB_minus parental JE2(WT), ermB_proficient strain (KES29), ermB_minus rae1 mutant (MNY205), ermB_proficient rae1 mutant (MNY212), ermB_minus purR mutant (MNY221), and ermB_proficient purR mutant (MNY224). Two culture media were used: A indicates tryptic soy broth (TSB), B indicates RPMI_1640 supplemented with 1% casamino acids.","dates":{"publication":"2026/04/12"},"accession":"GSE298918","cross_references":{"GSM":["GSM9025988","GSM9025989","GSM9025986","GSM9025987","GSM9025984","GSM9025985","GSM9025982","GSM9026015","GSM9025983","GSM9026013","GSM9025980","GSM9026014","GSM9025981","GSM9026011","GSM9026012","GSM9026010","GSM9025999","GSM9026008","GSM9025997","GSM9026009","GSM9025998","GSM9025995","GSM9026006","GSM9026007","GSM9025996","GSM9025993","GSM9026004","GSM9026005","GSM9025994","GSM9026002","GSM9025991","GSM9026003","GSM9025992","GSM9026000","GSM9025990","GSM9026001"],"GPL":["17452"],"GSE":["298918"],"taxon":["Staphylococcus aureus"]}}