GEOapplication/xmlftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE298nnn/GSE298918/primaryOK200TranscriptomicsStaphylococcus aureusExpression profiling by high throughput sequencinghttps://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE298918GEOGSEfalseThe role of PurR purine transcriptional repressor and Rae1 endoribonuclease in Erm-mediated macrolide resistance in methicilin-resistant Staphylococcus aureus.Differential gene expression between six S. aureus strains were determined by RNA-seq in 3 biological replicates.The six strains are ermB_minus parental JE2(WT), ermB_proficient strain (KES29), ermB_minus rae1 mutant (MNY205), ermB_proficient rae1 mutant (MNY212), ermB_minus purR mutant (MNY221), and ermB_proficient purR mutant (MNY224). Two culture media were used: A indicates tryptic soy broth (TSB), B indicates RPMI_1640 supplemented with 1% casamino acids.2026/04/12GSE298918GSM9025988GSM9025989GSM9025986GSM9025987GSM9025984GSM9025985GSM9025982GSM9026015GSM9025983GSM9026013GSM9025980GSM9026014GSM9025981GSM9026011GSM9026012GSM9026010GSM9025999GSM9026008GSM9025997GSM9026009GSM9025998GSM9026006GSM9025995GSM9026007GSM9025996GSM9025993GSM9026004GSM9026005GSM9025994GSM9026002GSM9025991GSM9026003GSM9025992GSM9026000GSM9025990GSM902600117452298918Staphylococcus aureus