{"database":"GEO","file_versions":[{"headers":{"Content-Type":["application/json"]},"body":{"files":{"Other":["ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE299nnn/GSE299449/"]},"type":"primary"},"statusCodeValue":200,"statusCode":"OK"}],"scores":null,"additional":{"omics_type":["Transcriptomics"],"species":["Mus musculus"],"gds_type":["Expression profiling by high throughput sequencing"],"full_dataset_link":["https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE299449"],"repository":["GEO"],"entry_type":["GSE"],"additional_accession":[]},"is_claimable":false,"name":"Engineering a Lipid Nanoparticle with Atypical Calcium Crystal Structure for Enhanced IFNβ-mediated Immunotherapy","description":"We have employed a single cell sequencing approach using 10x Genomics scRNAseq to study the anti-tumoral effects of NanoCa. Our results have shown that NanoCa activates the innate immune response by inducing IFNβ, to investigate which types of cells are involved in the anti-tumor effect, CT26 tumor and Tumor-draining lymph nodes were isolated and analyzed using scRNA-seq.","dates":{"publication":"2026/06/09"},"accession":"GSE299449","cross_references":{"GSM":["GSM9039392","GSM9039393","GSM9039390","GSM9039391"],"GPL":["34328"],"GSE":["299449"],"taxon":["Mus musculus"]}}