GEOapplication/xmlftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE299nnn/GSE299622/primaryOK200TranscriptomicsHomo sapiensExpression profiling by high throughput sequencinghttps://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE299622GEOGSEfalseTranscriptome regulation in iPSC and astrocyte derived from CLN3 deficient patientCLN3 Batten disease is a severe pediatric neurodegenerative disorder caused by mutations in the CLN3 gene, most commonly a 1 kb deletion affecting exons 7 and 8. While research has focused on neuronal dysfunction, glial cells are increasingly recognized as key contributors to disease pathology. Here, we establish the iPSC and astrocyte model derived from a CLN3 patient fibrpblast cells with the 1 kb deletion and analyse the transcriptome regulation in both iPSC and astrocyte stages.2026/09/09GSE299622GSM9042130GSM9042131GSM9042120GSM9042121GSM9042122GSM9042123GSM9042124GSM9042125GSM9042126GSM9042127GSM9042128GSM904212923227299622Homo sapiens[42129767]