{"database":"GEO","file_versions":[{"headers":{"Content-Type":["application/json"]},"body":{"files":{"Other":["ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE299nnn/GSE299847/"]},"type":"primary"},"statusCode":"OK","statusCodeValue":200}],"scores":null,"additional":{"omics_type":["Transcriptomics"],"species":["Mus musculus"],"gds_type":["Expression profiling by high throughput sequencing"],"full_dataset_link":["https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE299847"],"repository":["GEO"],"entry_type":["GSE"],"additional_accession":[]},"is_claimable":false,"name":"Single Cell RNA Sequencing of immune cell populations from WT and Cdh5-cre Myct1 fl/fl mice","description":"We have examined single-cell sequencing using 10x Genomics scRNA-seq to study changes in the immune cell population from tumor-bearing Cdh5-cre Myct1 f/f mice. Previously, we identified that Myct1 is expressed in endothelial cells, and Myct1 deficiency reduces tumor angiogenesis, thereby enhancing the anti-tumor immune environment. This scRNA-seq provides a transcriptomic analysis of immune cells in the tumor microenvironment, showing how tumor angiogenesis affects immune cells in the tumor.","dates":{"publication":"2026/06/30"},"accession":"GSE299847","cross_references":{"GSM":["GSM9047728","GSM9047727"],"GPL":["19057"],"GSE":["299847"],"taxon":["Mus musculus"]}}