{"database":"GEO","file_versions":[{"headers":{"Content-Type":["application/json"]},"body":{"files":{"Other":["ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE300nnn/GSE300266/"]},"type":"primary"},"statusCode":"OK","statusCodeValue":200}],"scores":null,"additional":{"omics_type":["Transcriptomics"],"species":["Homo sapiens"],"gds_type":["Expression profiling by high throughput sequencing"],"full_dataset_link":["https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE300266"],"repository":["GEO"],"entry_type":["GSE"],"additional_accession":[]},"is_claimable":false,"name":"Short-Fiber Scaffold PGCL Stop Overgrowth for Endometrial Hyperplasia","description":"Endometrial hyperplasia (EH), a precursor to endometrial carcinoma, poses a major threat to women’s health. Current treatments are hindered by the poor adaptability of rigid levonorgestrel (LNG)-releasing intrauterine systems. To overcome this, By physically loading LNG into the base PGC scaffold, we constructed a drug-loaded PGCL scaffold with improved therapeutic function. To elucidate the underlying molecular mechanisms of PGCL scaffold therapy, we performed high-throughput RNA sequencing on Ishikawa cells treated with PGC and PGCL scaffolds, respectively.","dates":{"publication":"2026/06/30"},"accession":"GSE300266","cross_references":{"GSM":["GSM9056730","GSM9056731","GSM9056732","GSM9056733","GSM9056734","GSM9056735"],"GPL":["24676"],"GSE":["300266"],"taxon":["Homo sapiens"]}}