GEOapplication/xmlftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE300nnn/GSE300281/suppl/GSE300281_All_samples_normalized_counts.txt.gzftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE300nnn/GSE300281/suppl/filelist.txtftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE300nnn/GSE300281/suppl/GSE300281_RAW.tarftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE300nnn/GSE300281/primaryOK200TranscriptomicsMus musculusExpression profiling by high throughput sequencinghttps://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE300281GEOGSEfalseTranscriptional profiling of AGPS knockout breast cancer cells treated with TGF-BThis study investigates the transcriptional changes associated with depleting ether lipids via AGPS (alkylglycerone phosphate synthase) knockout in epithelial PyMT-1099 murine breast cancer cells. RNA-Seq was performed to compare the gene expression profiles between AGPS knockout and control cells, both in the presence and absence of TGF-B treatment. The data provide insights into how ether lipid metabolism intersects with TGF-B-mediated signaling pathways and epithelial-to-mesenchymal transition (EMT) in breast cancer.2026/06/18GSE300281GSM9057377GSM9057376GSM9057379GSM9057378GSM9057380GSM9057373GSM9057375GSM905737417021300281Mus musculus