{"database":"GEO","file_versions":[{"headers":{"Content-Type":["application/json"]},"body":{"files":{"Other":["ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE300nnn/GSE300551/"]},"type":"primary"},"statusCode":"OK","statusCodeValue":200}],"scores":null,"additional":{"omics_type":["Transcriptomics"],"species":[" Mus musculus","Homo sapiens"],"gds_type":[" Other","Expression profiling by high throughput sequencing"],"full_dataset_link":["https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE300551"],"repository":["GEO"],"entry_type":["GSE"],"additional_accession":[]},"is_claimable":false,"name":"Massively multiplex multi-modal chemical screens at single-cell resolution with icCITE-plex","description":"We present icCITE-plex, a novel cellular barcoding systems that enable multiplexed analysis of multiple independent samples within a single experiment through a combination of viral barcodes and antibody-based plate-barcodes. Using this platform, we successfully profiled 360 drug-dose responses across 475 surface proteins, 64 intracellular epitopes, and the whole transcriptome in human and mouse T cells treated with 56 different kinase inhibitors, demonstrating the method's ability to capture multi-modal cellular responses to chemical perturbations.","dates":{"publication":"2026/04/14"},"accession":"GSE300551","cross_references":{"GSM":["GSM9064448","GSM9064449","GSM9064468","GSM9064446","GSM9064447","GSM9064469","GSM9064455","GSM9064456","GSM9064453","GSM9064454","GSM9064451","GSM9064452","GSM9064450","GSM9064459","GSM9064457","GSM9064458","GSM9064466","GSM9064467","GSM9064445","GSM9064464","GSM9064465","GSM9064462","GSM9064463","GSM9064460","GSM9064461"],"GPL":["25526"],"GSE":["300551"],"taxon":[" Mus musculus","Homo sapiens"]}}