GEOapplication/xmlftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE300nnn/GSE300655/primaryOK200TranscriptomicsMus musculusExpression profiling by high throughput sequencinghttps://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE300655GEOGSEfalseExpression data of E13.5 placenta from intra-cytoplasmic sperm injection(ICSI)-F2 offspringVarious behavioural abnormalities and congenital anomalies were observed in the F2 offspring of ICSI (Kanatsu-Shinohara et al., 2023, J. Clin.). Invest. 133(22): e170140). The data presented here aim to clarify the cause of these abnormalities. Gene expression in the ICSI-F2 placenta was investigated using RNA sequencing (RNA-seq). ICSI was performed using C57BL/6 epididymal sperm and oocytes. Male ICSI-F2 offspring was mated with wild-type C57BL/6 female, and placentae recovered from pregnant females at E13.5 were examined for gene expression. Each group contains five biological replicates.2026/04/21GSE300655GSM9065878GSM9065879GSM9065876GSM9065877GSM9065875GSM9065883GSM9065884GSM9065881GSM9065882GSM906588013112300655Mus musculus