{"database":"GEO","file_versions":[{"headers":{"Content-Type":["application/json"]},"body":{"files":{"Other":["ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE300nnn/GSE300718/"]},"type":"primary"},"statusCode":"OK","statusCodeValue":200}],"scores":null,"additional":{"omics_type":["Genomics"],"species":["Mus musculus"],"gds_type":["Non-coding RNA profiling by high throughput sequencing"],"full_dataset_link":["https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE300718"],"repository":["GEO"],"entry_type":["GSE"],"additional_accession":[]},"is_claimable":false,"name":"Small RNA production in E13.5 placenta of intra-cytoplasmic sperm injection(ICSI)-F2 offspring","description":"Various behavioural abnormalities were observed in the F2 offspring of ICSI (Kanatsu-Shinohara et al., 2023, J. Clin. Invest. 133(22):e170140). The data presented here aim to clarify the cause of these abnormalities, and gene expression in the neonatal brain was investigated using RNA sequencing (RNAseq). ICSI was performed using C57BL/6 epididymal sperm and oocytes. Males from the F1 generation were naturally mated with C57BL/6 females to produce the F2 generation. Small RNA production in E13.5 placenta of ICSI-F2 offspring was examined. Each group contains 5 biological replicates.","dates":{"publication":"2026/04/21"},"accession":"GSE300718","cross_references":{"GSM":["GSM9067187","GSM9067186","GSM9067185","GSM9067184","GSM9067183","GSM9067182","GSM9067181","GSM9067190","GSM9067189","GSM9067188"],"GPL":["34328"],"GSE":["300718"],"taxon":["Mus musculus"]}}