{"database":"GEO","file_versions":[{"headers":{"Content-Type":["application/json"]},"body":{"files":{"Other":["ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE300nnn/GSE300746/"]},"type":"primary"},"statusCode":"OK","statusCodeValue":200}],"scores":null,"additional":{"omics_type":["Transcriptomics"],"species":["Mus musculus"],"gds_type":["Expression profiling by high throughput sequencing"],"full_dataset_link":["https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE300746"],"repository":["GEO"],"entry_type":["GSE"],"additional_accession":[]},"is_claimable":false,"name":"RNA-Seq Profiling of Kidney Responses in Wild-Type and Angpt2 Knockout Mice Following a 3-Week Adenine Diet","description":"Chronic kidney disease (CKD) is characterized by progressive tubulointerstitial injury, which plays a critical role in renal dysfunction. Angiopoietin-2 (Angpt2) is implicated in vascular and inflammatory processes, but its role in CKD remains unclear. In this study, we performed RNA-seq to analyze gene expression differences in the kidneys of wild-type and Angpt2 knockout mice after a 3-week adenine diet, a well-established model of tubulointerstitial injury.","dates":{"publication":"2026/04/29"},"accession":"GSE300746","cross_references":{"GSM":["GSM9067660","GSM9067659","GSM9067658","GSM9067657","GSM9067656","GSM9067661"],"GPL":["24247"],"GSE":["300746"],"taxon":["Mus musculus"]}}