{"database":"GEO","file_versions":[{"headers":{"Content-Type":["application/json"]},"body":{"files":{"Other":["ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE300nnn/GSE300943/"]},"type":"primary"},"statusCode":"OK","statusCodeValue":200}],"scores":null,"additional":{"omics_type":["Other"],"species":["Homo sapiens"],"gds_type":["Other"],"full_dataset_link":["https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE300943"],"repository":["GEO"],"entry_type":["GSE"],"additional_accession":[]},"is_claimable":false,"name":"Analysis of chromosomal structual aberratons in U-937 cell line","description":"This Hi-C experiment was a part of a research which analyzed chromosomal structural aberrations in hematological malignancies. First, the author conducted comprehensive detection of fusion transcripts in RNA-seq data of DSMZ’s 99 cell lines, and then picked up cell lines with characteristic complex karyotype. U-937 cell line is one of them, which shows several characteristic “high-intensity bands” in contact maps. This Hi-C experiment revealed ectopic gene amplifications of cancer-associated genes.","dates":{"publication":"2026/06/14"},"accession":"GSE300943","cross_references":{"GSM":["GSM9072538"],"GPL":["24676"],"GSE":["300943"],"taxon":["Homo sapiens"]}}