GEOapplication/xmlftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE300nnn/GSE300943/primaryOK200OtherHomo sapiensOtherhttps://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE300943GEOGSEfalseAnalysis of chromosomal structual aberratons in U-937 cell lineThis Hi-C experiment was a part of a research which analyzed chromosomal structural aberrations in hematological malignancies. First, the author conducted comprehensive detection of fusion transcripts in RNA-seq data of DSMZ’s 99 cell lines, and then picked up cell lines with characteristic complex karyotype. U-937 cell line is one of them, which shows several characteristic “high-intensity bands” in contact maps. This Hi-C experiment revealed ectopic gene amplifications of cancer-associated genes.2026/06/14GSE300943GSM907253824676300943Homo sapiens