{"database":"GEO","file_versions":[{"headers":{"Content-Type":["application/json"]},"body":{"files":{"Other":["ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE300nnn/GSE300991/"]},"type":"primary"},"statusCode":"OK","statusCodeValue":200}],"scores":null,"additional":{"omics_type":["Transcriptomics"],"species":["Mus musculus"],"gds_type":["Expression profiling by high throughput sequencing"],"full_dataset_link":["https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE300991"],"repository":["GEO"],"entry_type":["GSE"],"additional_accession":[]},"is_claimable":false,"name":"Single-cell RNA-seq analysis was performed on CD45-positive cells isolated from mouse mammary tumors.","description":"Tumors derived from BP cells of mouse mammary cancer were collected after treatment with vehicle control, olaparib alone, or the combination of olaparib and an IRG1 inhibitor. CD45-positive cells were isolated from these tumors for single-cell RNA-seq analysis to investigate the impact of the combination therapy on the tumor immune microenvironment.","dates":{"publication":"2026/02/24"},"accession":"GSE300991","cross_references":{"GSM":["GSM9073319","GSM9073321","GSM9073320"],"GPL":["34290"],"GSE":["300991"],"taxon":["Mus musculus"],"PMID":["[41279612]"]}}