GEOTranscriptomicsMus musculusExpression profiling by high throughput sequencinghttps://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE301044GEOGSEfalseHTR2B Enhances the Phagocytosis of Brain Macrophages and Alleviates Brain Injury after StrokeThis study employs single-cell RNA sequencing to investigate the dynamic changes in monocytic-macrophage populations in the brain following ischemic stroke. We analyzed brain tissues from mice subjected to middle cerebral artery occlusion (MCAO) for 3 days. Additionally, we compared the macrophage transcriptomes between Htr2bfl/fl and Lyz2creHtr2b mice to elucidate the impact of HTR2B deficiency on macrophage responses 3d-post-stroke. Our findings provide novel insights into the role of HTR2B in regulating macrophage behavior and its potential implications in stroke pathogenesis and recovery.2026/06/01GSE301044GSM9074155GSM907415624247301044Mus musculus