{"database":"GEO","file_versions":[{"headers":{"Content-Type":["application/json"]},"body":{"files":{"Other":["ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE301nnn/GSE301093/"]},"type":"primary"},"statusCode":"OK","statusCodeValue":200}],"scores":null,"additional":{"omics_type":["Transcriptomics"],"species":["Mus musculus"],"gds_type":["Expression profiling by high throughput sequencing"],"full_dataset_link":["https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE301093"],"repository":["GEO"],"entry_type":["GSE"],"additional_accession":[]},"is_claimable":false,"name":"Effect of brain-derived EV from PS19 and PS19_P2rx7 knockout mice on gene expression in microglia from WT mice","description":"P2rx7 is an ATP-gated ion-channel, known to play pivotal roles in neuroinflammation and tauopathies, although its mechanisms are yet to be elucidated. In this study we investigated the effect of intracranial injection of brain-derived EVs (BDEVs) from P2rx7 deficient tauopathy mouse in microglia transcriptomics. This dataset is part of BioProject PRJNA1281629, which includes bulk and single-cell RNAseq experiments.","dates":{"publication":"2026/09/21"},"accession":"GSE301093","cross_references":{"GSM":["GSM9075181","GSM9075182","GSM9075183","GSM9075184","GSM9075180","GSM9075178","GSM9075179","GSM9075185","GSM9075174","GSM9075175","GSM9075186","GSM9075176","GSM9075187","GSM9075177"],"GPL":["34328"],"GSE":["301093"],"taxon":["Mus musculus"]}}