GEOapplication/xmlftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE301nnn/GSE301093/primaryOK200TranscriptomicsMus musculusExpression profiling by high throughput sequencinghttps://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE301093GEOGSEfalseEffect of brain-derived EV from PS19 and PS19_P2rx7 knockout mice on gene expression in microglia from WT miceP2rx7 is an ATP-gated ion-channel, known to play pivotal roles in neuroinflammation and tauopathies, although its mechanisms are yet to be elucidated. In this study we investigated the effect of intracranial injection of brain-derived EVs (BDEVs) from P2rx7 deficient tauopathy mouse in microglia transcriptomics. This dataset is part of BioProject PRJNA1281629, which includes bulk and single-cell RNAseq experiments.2026/09/21GSE301093GSM9075181GSM9075182GSM9075183GSM9075184GSM9075180GSM9075178GSM9075179GSM9075185GSM9075174GSM9075175GSM9075186GSM9075176GSM9075187GSM907517734328301093Mus musculus