{"database":"GEO","file_versions":[{"headers":{"Content-Type":["application/json"]},"body":{"files":{"Other":["ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE301nnn/GSE301235/"]},"type":"primary"},"statusCode":"OK","statusCodeValue":200}],"scores":null,"additional":{"omics_type":["Methylation profiling"],"species":["Mus musculus"],"gds_type":["Methylation profiling by high throughput sequencing"],"full_dataset_link":["https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE301235"],"repository":["GEO"],"entry_type":["GSE"],"additional_accession":[]},"is_claimable":false,"name":"DNA methylation predicts hippocampus-dependent long-term memory, but not memory updating","description":"DNA methylation-based epigenetic clocks estimate biological age and (in combination with clinical biomarkers) can predict complex behavioral phenotypes. We established a methylation clock highly predictive of chronological age, as well as two methylation predictors for long-term memory performance. CpG sites that accurately predicted chronological age were distinct from sites predictive of long-term memory performance, suggesting specific methylation signatures underlie cognitive function independent of aging.","dates":{"publication":"2026/06/30"},"accession":"GSE301235","cross_references":{"GSM":["GSM9078451","GSM9078450","GSM9078413","GSM9078457","GSM9078456","GSM9078412","GSM9078459","GSM9078415","GSM9078414","GSM9078458","GSM9078453","GSM9078452","GSM9078411","GSM9078455","GSM9078410","GSM9078454","GSM9078409","GSM9078406","GSM9078405","GSM9078449","GSM9078408","GSM9078407","GSM9078460","GSM9078462","GSM9078461","GSM9078424","GSM9078423","GSM9078426","GSM9078425","GSM9078420","GSM9078422","GSM9078421","GSM9078417","GSM9078416","GSM9078419","GSM9078418","GSM9078435","GSM9078434","GSM9078437","GSM9078436","GSM9078431","GSM9078430","GSM9078433","GSM9078432","GSM9078428","GSM9078427","GSM9078429","GSM9078440","GSM9078446","GSM9078445","GSM9078404","GSM9078448","GSM9078447","GSM9078403","GSM9078442","GSM9078441","GSM9078444","GSM9078443","GSM9078439","GSM9078438"],"GPL":["24247"],"GSE":["301235"],"taxon":["Mus musculus"]}}