GEOapplication/xmlftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE301nnn/GSE301235/primaryOK200Methylation profilingMus musculusMethylation profiling by high throughput sequencinghttps://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE301235GEOGSEfalseDNA methylation predicts hippocampus-dependent long-term memory, but not memory updatingDNA methylation-based epigenetic clocks estimate biological age and (in combination with clinical biomarkers) can predict complex behavioral phenotypes. We established a methylation clock highly predictive of chronological age, as well as two methylation predictors for long-term memory performance. CpG sites that accurately predicted chronological age were distinct from sites predictive of long-term memory performance, suggesting specific methylation signatures underlie cognitive function independent of aging.2026/06/30GSE301235GSM9078451GSM9078450GSM9078413GSM9078457GSM9078456GSM9078412GSM9078459GSM9078415GSM9078414GSM9078458GSM9078453GSM9078452GSM9078411GSM9078455GSM9078410GSM9078454GSM9078409GSM9078406GSM9078405GSM9078449GSM9078408GSM9078407GSM9078460GSM9078462GSM9078461GSM9078424GSM9078423GSM9078426GSM9078425GSM9078420GSM9078422GSM9078421GSM9078417GSM9078416GSM9078419GSM9078418GSM9078435GSM9078434GSM9078437GSM9078436GSM9078431GSM9078430GSM9078433GSM9078432GSM9078428GSM9078427GSM9078429GSM9078440GSM9078446GSM9078445GSM9078404GSM9078448GSM9078447GSM9078403GSM9078442GSM9078441GSM9078444GSM9078443GSM9078439GSM907843824247301235Mus musculus