{"database":"GEO","file_versions":[{"headers":{"Content-Type":["application/json"]},"body":{"files":{"Other":["ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE301nnn/GSE301378/"]},"type":"primary"},"statusCode":"OK","statusCodeValue":200}],"scores":null,"additional":{"omics_type":["Transcriptomics"],"species":["Homo sapiens"],"gds_type":[" Other","Expression profiling by high throughput sequencing"],"full_dataset_link":["https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE301378"],"repository":["GEO"],"entry_type":["GSE"],"additional_accession":[]},"is_claimable":false,"name":"Single-cell RNA-seq and TCR profiling of tissue-resident memory T cells in the fallopian tube and matched ovarian cancer samples","description":"This study investigates the immune characteristics of tissue-resident memory T cells in the human fallopian tube in high-grade serous ovarian cancer (HGSOC). Single-cell RNA sequencing (scRNA-seq) and paired T-cell receptor sequencing (scTCR-seq) were performed on samples from non-cancerous fallopian tube tissue, metastatic omental tumors, and peripheral blood from HGSOC patients. The dataset enables analysis of tissue-resident T cell populations, clonal relationships across tissues, and immune features associated with tumor progression. These data provide a resource for studying tissue-resident T cell heterogeneity, clonal expansion, and tumor-associated immune responses in ovarian cancer.","dates":{"publication":"2026/04/03"},"accession":"GSE301378","cross_references":{"GSM":["GSM9081840","GSM9081841","GSM9081820","GSM9081842","GSM9081843","GSM9081821","GSM9081844","GSM9081822","GSM9081823","GSM9081845","GSM9081846","GSM9081824","GSM9081847","GSM9081825","GSM9081826","GSM9081848","GSM9081849","GSM9081827","GSM9081828","GSM9081829","GSM9081850","GSM9081851","GSM9081830","GSM9081831","GSM9081832","GSM9081833","GSM9081834","GSM9081835","GSM9081836","GSM9081837","GSM9081838","GSM9081839"],"GPL":["34284"],"GSE":["301378"],"taxon":["Homo sapiens"]}}