GEOapplication/xmlftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE301nnn/GSE301378/primaryOK200TranscriptomicsHomo sapiens OtherExpression profiling by high throughput sequencinghttps://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE301378GEOGSEfalseSingle-cell RNA-seq and TCR profiling of tissue-resident memory T cells in the fallopian tube and matched ovarian cancer samplesThis study investigates the immune characteristics of tissue-resident memory T cells in the human fallopian tube in high-grade serous ovarian cancer (HGSOC). Single-cell RNA sequencing (scRNA-seq) and paired T-cell receptor sequencing (scTCR-seq) were performed on samples from non-cancerous fallopian tube tissue, metastatic omental tumors, and peripheral blood from HGSOC patients. The dataset enables analysis of tissue-resident T cell populations, clonal relationships across tissues, and immune features associated with tumor progression. These data provide a resource for studying tissue-resident T cell heterogeneity, clonal expansion, and tumor-associated immune responses in ovarian cancer.2026/04/03GSE301378GSM9081840GSM9081841GSM9081820GSM9081842GSM9081843GSM9081821GSM9081844GSM9081822GSM9081823GSM9081845GSM9081846GSM9081824GSM9081847GSM9081825GSM9081826GSM9081848GSM9081849GSM9081827GSM9081828GSM9081829GSM9081850GSM9081851GSM9081830GSM9081831GSM9081832GSM9081833GSM9081834GSM9081835GSM9081836GSM9081837GSM9081838GSM908183934284301378Homo sapiens