GEOapplication/xmlftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE301nnn/GSE301649/primaryOK200TranscriptomicsRattus norvegicusExpression profiling by high throughput sequencinghttps://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE301649GEOGSEfalseRNA Sequencing of HMGB1-Driven Proliferation and Migration in Pulmonary Arterial Smooth Muscle CellsPrevious studies have demonstrated that HMGB1, functioning as a Damage-Associated Molecular Pattern (DAMP) molecule, is implicated in the pathological process of pulmonary arterial hypertension (PAH). The current study further investigated the underlying signaling pathways through which HMGB1 contributes to PAH. Transcriptomic analysis revealed HMGB1-associated differentially expressed genes (DEGs). Gene Ontology (GO) enrichment analysis identified relevant transcriptomic pathways involved in HMGB1-mediated promotion of PAH.2026/08/19GSE301649GSM9086910GSM9086904GSM9086903GSM9086902GSM9086908GSM9086907GSM9086906GSM9086905GSM908690918694301649Rattus norvegicus[42215667]