GEOapplication/xmlftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE301nnn/GSE301771/primaryOK200TranscriptomicsHomo sapiens OtherExpression profiling by high throughput sequencinghttps://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE301771GEOGSEfalseSingle-cell profiling of human liver and peripheral-blood γδ T cells according to HCMV serostatusThis study generated single-cell transcriptomic and surface-protein datasets to examine the heterogeneity of human liver sinusoidal γδ T cells and their association with latent human cytomegalovirus infection. γδ T cells isolated from liver perfusates of healthy living donors were profiled using single-cell RNA sequencing with antibody-derived tags. The dataset includes Vγ9Vδ2 and non-Vγ9Vδ2 γδ T-cell populations from HCMV-seropositive and HCMV-seronegative donors and enables comparison of their transcriptional states, surface phenotypes, differentiation patterns, and TCR repertoires. Paired peripheral-blood γδ T-cell samples were additionally profiled for comparison with liver-derived populations.eir diverse functions.2026/07/27GSE301771GSM9595776GSM9595775GSM9595778GSM9595777GSM9595780GSM9089261GSM9089263GSM9089253GSM9089270GSM9089258GSM9595779GSM9089265GSM9089256GSM90892682079534281301771Homo sapiens