{"database":"GEO","file_versions":[{"headers":{"Content-Type":["application/json"]},"body":{"files":{"Other":["ftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE302nnn/GSE302049/"]},"type":"primary"},"statusCode":"OK","statusCodeValue":200}],"scores":null,"additional":{"omics_type":["Transcriptomics"],"species":["Homo sapiens"],"gds_type":["Expression profiling by array"],"full_dataset_link":["https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE302049"],"repository":["GEO"],"entry_type":["GSE"],"additional_accession":[]},"is_claimable":false,"name":"Analysis of gene expression after RNAi (siPool)-mediated knockdown of TEDAR (LINC00302) lncRNA in primary human keratinocytes","description":"Long non-coding RNAs (lncRNAs) are emerging as key regulators of epidermal differentiation. To investigate the function of the skin-enriched lncRNA TEDAR (LINC00302), we performed RNAi (siPool)-mediated knockdown in 3D organotypic skin models and analyzed changes in gene expression using the GeneChip™ Human Transcriptome Array 2.0 microarray platform. Differential expression analysis demosntrated that TEDAR regulated genes involved in late epidermal differentiation and barrier formation.","dates":{"publication":"2026/07/01"},"accession":"GSE302049","cross_references":{"GSM":["GSM9094820","GSM9094815","GSM9094816","GSM9094817","GSM9094818","GSM9094819"],"GPL":["17586"],"GSE":["302049"],"taxon":["Homo sapiens"]}}