GEOapplication/xmlftp://ftp.ncbi.nlm.nih.gov/geo/series/GSE302nnn/GSE302685/primaryOK200GenomicsMus musculusGenome binding/occupancy profiling by high throughput sequencing Expression profiling by high throughput sequencinghttps://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE302685GEOGSEfalseInflammatory memory primes the intestine for enhanced regenerative potential [multiome 1]Intestinal regeneration after injury can occur through the expansion of surviving intestinal stem cells (ISCs) or via dedifferentiation of progenitor cells. To assess whether Lgr5⁺ ISCs that persist after irradiation—and their progeny—undergo long-term transcriptomic and epigenetic alterations, we performed single-cell multiome sequencing (scRNA-seq and scATAC-seq) using the 10x Genomics Chromium platform.2026/09/16GSE302685GSM9108856GSM9108857GSM9108858GSM910885924247302685Mus musculus